Search results for " forensic toxicology"

showing 3 items of 3 documents

A fatal case of a paint thinner ingestion: Comparison between toxicological and histological findings

2010

Toluene and xylene are aromatic hydrocarbons commonly used as an industrial solvent for the manufacturing of pharmaceuticals, paints, and chemicals. The Occupational Safety and Health Administration has determined that toluene levels of 2000 parts per million (ppm) are considered dangerous to life and health. Several studies have examined the absorption of toluene and xylene following inhalation and oral ingestion in humans. Volatile organic compounds that are absorbed into the blood are distributed throughout the body; in particular, distribution of absorbed toluene and xylene in humans and rodents is characterized by preferential uptake in well-perfused and lipophil tissues such as the br…

MaleAdolescent2734XylenePoison controlPaint thinnerBrain EdemaHemorrhagePulmonary EdemaAbsorption (skin)XylenesEsophaguKidneyGas Chromatography-Mass SpectrometryPathology and Forensic Medicinetoluene xilene paint thinner ingestion self poisoning varnish-diluting solventsToxicologychemistry.chemical_compoundForensic ToxicologyEsophagusSettore MED/43 - Medicina LegalePaint thinner ingestionSelf poisoningIngestionHumansGastrointestinal ContentForensic PathologyLungSolid Phase MicroextractionChromatographyChemistryXyleneForensic toxicologyBrainTolueneGastrointestinal ContentsSuicideLiverSolventSolventsPaint thinner ingestion; Self poisoning; Toluene; Varnish-diluting solvents; Xylene; Adolescent; Brain; Brain Edema; Esophagus; Forensic Pathology; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Hemorrhage; Humans; Kidney; Liver; Lung; Male; Pulmonary Edema; Solid Phase Microextraction; Solvents; Toluene; Xylenes; Suicide; 2734Varnish-diluting solventGas chromatography–mass spectrometryHumanToluene
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A possible biomarker for methadone related deaths

2017

Abstract Methadone (MTH) concentrations in those dying of MTH toxicity totally overlap concentrations where the presence of MTH is only an incidental finding, making it very difficult to make distinctions in actual cases. A biomarker, be it anatomical or biochemical for MTH toxicity is badly needed, particularly if that markers were known to disrupt effective ventilation. Because the brainstem houses the regulatory centers for cardiorespiratory-control enters, it would seem to be the most likely anatomical site to seek abnormalities in cardiorespiratory control. Objective To locate and describe the cells of nucleus of the solitary tract (TS)(NTS) in human brainstem and determine if neuronal…

MalePathologyNecrosisApoptosisAutopsyCohort Studies0302 clinical medicineRetrospective StudieMedicineForensic PathologyNeuronsPoisoningSolitary tractGeneral MedicineRostral ventrolateral medullaNecrosiImmunohistochemistryCaspase 9Narcotic030220 oncology & carcinogenesisToxicityFemaleBrainstemmedicine.symptomBrainstemCaspase-9HumanNarcoticsAdultProgrammed cell deathmedicine.medical_specialty2734Pathology and Forensic MedicineNecrosisForensic ToxicologyYoung Adult03 medical and health sciencesSettore MED/43 - Medicina LegaleSolitary NucleuSolitary NucleusNeurotoxicityHumansRetrospective Studiesbusiness.industryfungiApoptosiBiomarkerNeuronApoptosisApoptosis; Biomarker; Brainstem; Caspase-9; Methadone; Neurotoxicity; Adult; Apoptosis; Brain Stem; Caspase 9; Cohort Studies; Female; Forensic Pathology; Forensic Toxicology; Humans; Immunohistochemistry; Male; Methadone; Narcotics; Necrosis; Neurons; Poisoning; Retrospective Studies; Solitary Nucleus; Young Adult; 2734; LawCohort StudiebusinessLawMethadone030217 neurology & neurosurgeryBrain Stem
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Toxicological problems related to drugs with particular reference to chemical precursor

2013

the author analyze the toxicological problems related to drugs with particular reference to chemical precursor

frugs chemistry forensic toxicologySettore MED/43 - Medicina Legale
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